Bridging Phylogeny and Population genetics: Inferring divergence and selection at both interspecies and intraspecies level
Phylogeny studies inter-specific variations and typically describes the macroveolutionary changes of organisms over long time scales; population genetics instead typically focuses on the intra-species variability and describes microevolutionary changes occurred during the relatively recent history of a population. The two disciplines are characterised by different tools and methods, and too often phylogeneticists do not understand what population geneticists do, and vice versa. With this course we aim at stimulating a dialogue and a constructive discussion between students and teachers with phylogenetics, population genetics, but also ecological backgrounds, in such a way that we can appreciate the complementary nature of these disciplines. All students should be united by the will to understand better each other’s methodological processes. The aim is to form students that are capable of understanding both approaches and filling the gap between the two disciplines. We will do this by providing the theoretical and practical bases of both phylogenetics and population genetics. The course will cover some important applications such as detection of positive selection using PAML, site frequency spectrum analysis using Sweepfinder, inference of divergence time using BEAST, inference of population past demography using Fastsimcoal. Every day we will alternate topics on PHYLOgenetics, POPulation genetics, and a MIXture of them.